Compound Detail
CHEMBL1169827
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Basic Information
| ChEMBL ID | CHEMBL1169827 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SGRNBEGQBHHKMY-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
500.4
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 9.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor delta CHEMBL3979 | EC50 | 9.05 | 9.05 | 0.9 | 1 |
| Peroxisome proliferator-activated receptor delta CHEMBL2458 | EC50 | 8.64 | 8.64 | 2.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor delta | EC50 | = | 0.9 | nM | 9.05 | Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cell... | 21074432 |
| Peroxisome proliferator-activated receptor delta | EC50 | = | 2.3 | nM | 8.64 | Agonist activity at mouse PPAR-delta expressed in african green monkey CV-1 cell... | 21074432 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21074432 | 10.1016/j.bmcl.2010.10.103 | Mus musculus | 15 |
| 21074432 | 10.1016/j.bmcl.2010.10.103 | Peroxisome proliferator-activated receptor delta | 4 |
| 20542425 | 10.1016/j.bmcl.2010.05.094 | PPAR delta/gamma | 2 |
| 21074432 | 10.1016/j.bmcl.2010.10.103 | Peroxisome proliferator-activated receptor alpha | 2 |
| 21074432 | 10.1016/j.bmcl.2010.10.103 | Peroxisome proliferator-activated receptor gamma | 2 |
Data from ChEMBL 36 via Core Engine