Compound Detail
CHEMBL1202240
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1202240 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BIDLRCLLYKJSGE-UHFFFAOYSA-N |
| Parent Compound | CHEMBL146461 |
| Active Moiety | CHEMBL146461 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
219.3
MW (Da)
2.59
ALogP
2
HBA
1
HBD
23.5
PSA (Ų)
0.84
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 9.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A CHEMBL273 | Ki | 9.1 | 9.1 | 0.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Ki | = | 0.8 | nM | 9.1 | Displacement of [3H]-8-OH-DPAT from serotonin 5-HT1A receptor in Sprague-Dawley ... | 28943244 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 6418888 | 10.1021/jm00367a009 | Serotonin (5-HT) receptor | 3 |
| 28943244 | 10.1016/j.bmc.2017.09.018 | Mus musculus | 3 |
| 6418888 | 10.1021/jm00367a009 | Dopamine receptor | 2 |
| 28943244 | 10.1016/j.bmc.2017.09.018 | 5-hydroxytryptamine receptor 1A | 1 |
Data from ChEMBL 36 via Core Engine