Compound Detail
CHEMBL1203614
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1203614 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UCVQWFXXZWROOM-UHFFFAOYSA-N |
| Parent Compound | CHEMBL156517 |
| Active Moiety | CHEMBL156517 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
217.3
MW (Da)
2.56
ALogP
2
HBA
0
HBD
12.5
PSA (Ų)
0.72
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A CHEMBL273 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Ki | = | 3162.28 | nM | 5.5 | Binding affinity against 5-hydroxytryptamine 1A receptor in rat cerebral cortica... | 2153822 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2153822 | 10.1021/jm00164a026 | 5-hydroxytryptamine receptor 1A | 1 |
Data from ChEMBL 36 via Core Engine