Compound Detail
CHEMBL1221975
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC(C)(C)[Si](C)(C)O[C@H]1C=C2CCN3Cc4cc5c(cc4[C@H]([C@@H]1OC(=O)c1ccccc1)[C@@H]23)OCO5
Basic Information
| ChEMBL ID | CHEMBL1221975 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FPFREWZKIINHID-GWMMUDDPSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
505.7
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.41
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Acetylcholinesterase CHEMBL220 | Ki | 6.41 | 6.41 | 390.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Acetylcholinesterase | Ki | = | 390.0 | nM | 6.41 | Inhibition of AChE by Ellman's assay | 20655219 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20655219 | 10.1016/j.bmcl.2010.06.130 | Acetylcholinesterase | 1 |
Data from ChEMBL 36 via Core Engine