Compound Detail
CHEMBL122260
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Basic Information
| ChEMBL ID | CHEMBL122260 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FXOMCQMRHRJJTN-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
288.3
MW (Da)
1.78
ALogP
5
HBA
5
HBD
101.8
PSA (Ų)
0.55
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.01
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Epidermal growth factor receptor CHEMBL203 | IC50 | 5.01 | 5.01 | 9700.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Epidermal growth factor receptor | IC50 | = | 9700.0 | nM | 5.01 | Displacement of [gamma-32P]-ATP from Epidermal growth factor receptor in A431 ce... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(97)00014-0 | Epidermal growth factor receptor | 1 |
Data from ChEMBL 36 via Core Engine