Compound Detail
CHEMBL1223582
GLYCYBENZOFURAN Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1223582 |
| Name | GLYCYBENZOFURAN |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OEIIVGQLDAYZNT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
354.4
MW (Da)
5.04
ALogP
5
HBA
3
HBD
83.1
PSA (Ų)
0.57
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.59
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tyrosine-protein phosphatase non-receptor type 1 CHEMBL335 | IC50 | 4.59 | 4.59 | 25500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tyrosine-protein phosphatase non-receptor type 1 | IC50 | = | 25500.0 | nM | 4.59 | Inhibition of human recombinant PTP1B assessed as p-nitorphenol production after... | 20724155 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20724155 | 10.1016/j.bmcl.2010.07.110 | Tyrosine-protein phosphatase non-receptor type 1 | 5 |
| 24047800 | 10.1016/j.bmcl.2013.08.102 | Tyrosine-protein phosphatase non-receptor type 1 | 1 |
| 24047800 | 10.1016/j.bmcl.2013.08.102 | Dual specificity protein phosphatase 3 | 1 |
| 24047800 | 10.1016/j.bmcl.2013.08.102 | Tyrosine-protein phosphatase non-receptor type 2 | 1 |
Data from ChEMBL 36 via Core Engine