Compound Detail
CHEMBL1241361
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Basic Information
| ChEMBL ID | CHEMBL1241361 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FKLVKKGRGXWWCN-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
355.2
MW (Da)
3.39
ALogP
5
HBA
1
HBD
68.3
PSA (Ų)
0.68
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatitis C virus CHEMBL379 | EC50 | 5.52 | 5.52 | 3000.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatitis C virus | EC50 | = | 3000.0 | nM | 5.52 | Antiviral activity against HCV genotype 1a infected in Huh7.5 cells assessed as ... | 22059983 |
| Hepatitis C virus | EC50 | = | 3000.0 | nM | 5.52 | Antiviral activity against HCV genotype 1b infected in Ava5 cells assessed as in... | 22059983 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22059983 | 10.1021/jm201264t | Hepatitis C virus | 4 |
| 20047919 | 10.1128/aac.00614-09 | Cryptosporidium parvum | 2 |
| 20047919 | 10.1128/aac.00614-09 | HCT-8 | 2 |
| 22059983 | 10.1021/jm201264t | Unchecked | 2 |
| 22059983 | 10.1021/jm201264t | ADMET | 2 |
Data from ChEMBL 36 via Core Engine