Compound Detail
CHEMBL1241908
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Basic Information
| ChEMBL ID | CHEMBL1241908 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DAVIKTBRCQWOGT-GIJQJNRQSA-N |
2
Targets
4
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
293.3
MW (Da)
1.95
ALogP
5
HBA
1
HBD
84.6
PSA (Ų)
0.59
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 4 meas. best 4.86
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 4.86 | 4.86 | 13950.0 | 1 |
| Signal transducer and activator of transcription 5A CHEMBL5403 | IC50 | 4.33 | 4.33 | 47000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | IC50 | = | 13950.0 | nM | 4.86 | Antioxidant activity assessed as xanthin/xanthin oxidase superoxide scavengeing ... | 20576329 |
| Signal transducer and activator of transcription 5A | IC50 | = | 47000.0 | nM | 4.33 | Inhibition of STAT5 (unknown origin) | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20576329 | 10.1016/j.ejmech.2010.05.065 | NON-PROTEIN TARGET | 3 |
| - | 10.1039/C1MD00175B | Signal transducer and activator of transcription 5A | 1 |
| - | 10.1039/C1MD00175B | Signal transducer and activator of transcription 3 | 1 |
| - | 10.1039/C1MD00175B | Signal transducer and activator of transcription 1-alpha/beta | 1 |
Data from ChEMBL 36 via Core Engine