Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL1243407

ZINTEROL
🧪 Phase II
Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
🧪 Phase II
CC(C)(Cc1ccccc1)NCC(O)c1ccc(O)c(NS(C)(=O)=O)c1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL1243407
Name ZINTEROL
Phase Phase II
Structure Type MOL
InChI Key XJBCFFLVLOPYBV-UHFFFAOYSA-N

Known Names

Zinterol
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
1
Known Names

Molecular Properties

378.5
MW (Da)
2.41
ALogP
5
HBA
4
HBD
98.7
PSA (Ų)
0.53
QED
0
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Racemic
USAN Stem -terol
USAN Year 1977

Extended Properties

Molecular Formula C19H26N2O4S
MW 378.49
Aromatic Rings 2
Heavy Atoms 26
NP-Likeness -0.51

Activity Summary

EC50 1 meas. best 10.27

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Beta-2 adrenergic receptor
CHEMBL210
 EC50 10.27 10.27 0.1 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Beta-2 adrenergic receptor EC50 = 0.054 nM 10.27 Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO... 20804199

Literature References

PubMed DOI Target Context # Activities
20804199 10.1021/jm1005989 NON-PROTEIN TARGET 2
31486 10.1021/jm00207a015 Unchecked 2
- 10.6019/CHEMBL4651402 SARS-CoV-2 2
20804199 10.1021/jm1005989 No relevant target 1
20804199 10.1021/jm1005989 Unchecked 1
20804199 10.1021/jm1005989 Beta-2 adrenergic receptor 1

Data from ChEMBL 36 via Core Engine