Compound Detail
CHEMBL1256682
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Basic Information
| ChEMBL ID | CHEMBL1256682 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZNSZQJHTFRQUPD-UHFFFAOYSA-N |
1
Targets
7
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
349.6
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 7 meas. best 6.36
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | EC50 | 6.36 | 5.6 | 441.0 | 7 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | EC50 | = | 441.0 | nM | 6.36 | Antiproliferative activity against mouse neural precursor cells by MTT assay | 17417631 |
| NON-PROTEIN TARGET | EC50 | = | 1125.0 | nM | 5.95 | Antiproliferative activity against mouse medulloblastoma cells harboring heteroz... | 17417631 |
| NON-PROTEIN TARGET | EC50 | = | 1230.0 | nM | 5.91 | Antiproliferative activity against human GBM2 cells by MTT assay | 17417631 |
| NON-PROTEIN TARGET | EC50 | = | 1373.0 | nM | 5.86 | Antiproliferative activity against mouse neural precursor cells by colony format... | 17417631 |
| NON-PROTEIN TARGET | EC50 | = | 5815.0 | nM | 5.24 | Antiproliferative activity against mouse astrocyte cells by MTT assay | 17417631 |
| NON-PROTEIN TARGET | EC50 | = | 10580.0 | nM | 4.98 | Antiproliferative activity against human fetal neural precursor cells by MTT ass... | 17417631 |
| NON-PROTEIN TARGET | EC50 | = | 12630.0 | nM | 4.9 | Antiproliferative activity against human GBM1 cells by MTT assay | 17417631 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17417631 | 10.1038/nchembio873 | NON-PROTEIN TARGET | 8 |
| 17417631 | 10.1038/nchembio873 | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine