Assay Detail
Functional
CHEMBL1266183
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Antiproliferative activity against human GBM2 cells by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | GBM2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Chemical genetics reveals a complex functional ground state of neural stem cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 6.01 | 6.69 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL305187 | IFENPRODIL | 2.0 | 1 | 6.69 |
| CHEMBL53 | APOMORPHINE | 4.0 | 1 | 6.51 |
| CHEMBL1256693 | — | — | 1 | 6.51 |
| CHEMBL1256682 | — | — | 1 | 5.91 |
| CHEMBL73234 | CARBETAPENTANE | 4.0 | 1 | 5.76 |
| CHEMBL311158 | DIHYDROCAPSAICIN | — | 1 | 4.67 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL305187 | IFENPRODIL | EC50 | = | 206.0 | nM | 6.69 |
| CHEMBL53 | APOMORPHINE | EC50 | = | 310.0 | nM | 6.51 |
| CHEMBL1256693 | — | EC50 | = | 310.0 | nM | 6.51 |
| CHEMBL1256682 | — | EC50 | = | 1230.0 | nM | 5.91 |
| CHEMBL73234 | CARBETAPENTANE | EC50 | = | 1730.0 | nM | 5.76 |
| CHEMBL311158 | DIHYDROCAPSAICIN | EC50 | = | 21460.0 | nM | 4.67 |