Compound Detail
CHEMBL126589
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL126589 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FNSYWIPPPFVBAV-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
149.2
MW (Da)
0.85
ALogP
3
HBA
3
HBD
74.9
PSA (Ų)
0.52
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Urokinase-type plasminogen activator CHEMBL3286 | IC50 | 5.0 | 4.35 | 10000.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Urokinase-type plasminogen activator | IC50 | = | 10000.0 | nM | 5.0 | Inhibitory activity against Urokinase-type plasminogen activator | 11052791 |
| Urokinase-type plasminogen activator | IC50 | = | 200000.0 | nM | 3.7 | Inhibition of uPA | 18457385 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11052791 | 10.1021/jm0002228 | Urokinase-type plasminogen activator | 1 |
| 11052791 | 10.1021/jm0002228 | No relevant target | 1 |
| 18457385 | 10.1021/jm8000373 | Urokinase-type plasminogen activator | 1 |
Data from ChEMBL 36 via Core Engine