Compound Detail
CHEMBL128493
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Basic Information
| ChEMBL ID | CHEMBL128493 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RCPHAOPNVYGUBO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
330.5
MW (Da)
3.17
ALogP
3
HBA
0
HBD
32.8
PSA (Ų)
0.85
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 8.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cavia porcellus CHEMBL369 | EC50 | 8.89 | 8.89 | 1.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cavia porcellus | EC50 | = | 1.288 | nM | 8.89 | Inotropic responses, induced by the compound in electrically paced (Hz) guinea p... | 11708906 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11708906 | 10.1021/jm0155594 | Cavia porcellus | 2 |
Data from ChEMBL 36 via Core Engine