Compound Detail
CHEMBL129562
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Basic Information
| ChEMBL ID | CHEMBL129562 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HTANXWFGXPQIQT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
383.4
MW (Da)
3.37
ALogP
7
HBA
1
HBD
84.7
PSA (Ų)
0.70
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor gamma CHEMBL2459 | EC50 | 5.0 | 5.0 | 10000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor gamma | EC50 | = | 10000.0 | nM | 5.0 | In vitro transcriptional activation of Peroxisome proliferator activated recepto... | 8576907 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8576907 | 10.1021/jm950395a | Peroxisome proliferator-activated receptor gamma | 2 |
| 7966158 | 10.1021/jm00049a017 | Mus musculus | 1 |
| 8576907 | 10.1021/jm950395a | Peroxisome proliferator-activated receptor alpha | 1 |
| 8576907 | 10.1021/jm950395a | Peroxisome proliferator-activated receptor delta | 1 |
| 8576907 | 10.1021/jm950395a | Mus musculus | 1 |
Data from ChEMBL 36 via Core Engine