Compound Detail
CHEMBL129680
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Basic Information
| ChEMBL ID | CHEMBL129680 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UIUZIOPTAVDIIT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
313.5
MW (Da)
3.48
ALogP
3
HBA
3
HBD
81.1
PSA (Ų)
0.36
QED
0
Ro5 Violations
17
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 9.47
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cavia porcellus CHEMBL369 | EC50 | 9.47 | 9.47 | 0.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cavia porcellus | EC50 | = | 0.3388 | nM | 9.47 | Inotropic responses, induced by the compound in electrically paced (Hz) guinea p... | 11708906 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11708906 | 10.1021/jm0155594 | Cavia porcellus | 2 |
| 11708906 | 10.1021/jm0155594 | Muscarinic acetylcholine receptor M1 | 1 |
| 11708906 | 10.1021/jm0155594 | Muscarinic acetylcholine receptor M2 | 1 |
| 11708906 | 10.1021/jm0155594 | Muscarinic acetylcholine receptor M3 | 1 |
| 11708906 | 10.1021/jm0155594 | Muscarinic acetylcholine receptor M4 | 1 |
| 11708906 | 10.1021/jm0155594 | Muscarinic acetylcholine receptor M5 | 1 |
Data from ChEMBL 36 via Core Engine