Compound Detail
CHEMBL1327262
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1327262 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AJQYPYYWHFOFPK-UHFFFAOYSA-N |
| Parent Compound | CHEMBL1617632 |
| Active Moiety | CHEMBL1617632 |
3
Targets
3
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
191.2
MW (Da)
1.07
ALogP
3
HBA
3
HBD
74.9
PSA (Ų)
0.64
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.36
IC50 1 meas. best 5.56
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.56 | 5.56 | 2740.0 | 1 |
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 5.36 | 5.36 | 4349.0 | 1 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 4.44 | 4.44 | 36684.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 2740.0 | nM | 5.56 | PUBCHEM_BIOASSAY: A biochemical assay using the ADP-Hunter methodology, purified... | - |
| Zinc finger protein mex-5 | EC50 | = | 4349.0 | nM | 5.36 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| RNA-binding protein pos-1 | EC50 | = | 36684.0 | nM | 4.44 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
Data from ChEMBL 36 via Core Engine