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Compound Detail

CHEMBL1331809

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CCOC(=O)C(C(C)=O)c1c(Br)c(O)c(O)c2c(C(=O)c3ccc(C)cc3)coc12

Basic Information

ChEMBL ID CHEMBL1331809
Phase Preclinical
Structure Type MOL
InChI Key UYUXWHJPWJUMJI-UHFFFAOYSA-N
1
Targets
6
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

475.3
MW (Da)
4.38
ALogP
7
HBA
2
HBD
114.0
PSA (Ų)
0.24
QED
0
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C22H19BrO7
MW 475.29
Aromatic Rings 3
Heavy Atoms 30
NP-Likeness 0.25

Activity Summary

EC50 4 meas. best 5.47
IC50 2 meas. best 5.46

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
EC50 5.47 5.105 3410.0 4
Unchecked
CHEMBL612545
IC50 5.46 5.415 3430.0 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine