Compound Detail
CHEMBL134215
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Basic Information
| ChEMBL ID | CHEMBL134215 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IUZSSWYFWLRALF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
307.5
MW (Da)
5.26
ALogP
1
HBA
0
HBD
3.2
PSA (Ų)
0.70
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sigma non-opioid intracellular receptor 1 CHEMBL287 | IC50 | 7.89 | 7.89 | 12.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Sigma non-opioid intracellular receptor 1 | IC50 | = | 12.88 | nM | 7.89 | The compound was tested for affinity towards sigma-3 receptor | 7990111 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7990111 | 10.1021/jm00050a008 | Sigma non-opioid intracellular receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine