Compound Detail
CHEMBL1356350
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Basic Information
| ChEMBL ID | CHEMBL1356350 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DMMXXRSIPNMYTQ-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
349.5
MW (Da)
2.27
ALogP
4
HBA
2
HBD
92.5
PSA (Ų)
0.88
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 4.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 4.52 | 4.52 | 30065.0 | 1 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 4.48 | 4.48 | 33351.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Zinc finger protein mex-5 | EC50 | = | 30065.0 | nM | 4.52 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| RNA-binding protein pos-1 | EC50 | = | 33351.0 | nM | 4.48 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24583350 | 10.1016/j.ejmech.2014.02.028 | Mycobacterium tuberculosis | 2 |
| 24583350 | 10.1016/j.ejmech.2014.02.028 | RAW264.7 | 1 |
Data from ChEMBL 36 via Core Engine