Compound Detail
CHEMBL1365898
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Basic Information
| ChEMBL ID | CHEMBL1365898 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YIHOMAXYJIKXIL-ZYMOGRSISA-N |
3
Targets
4
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
349.8
MW (Da)
2.70
ALogP
5
HBA
1
HBD
100.6
PSA (Ų)
0.84
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 4 meas. best 5.09
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 5.09 | 5.065 | 8140.0 | 2 |
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 4.94 | 4.94 | 11560.0 | 1 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 4.9 | 4.9 | 12499.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 8140.0 | nM | 5.09 | PUBCHEM_BIOASSAY: HCS for Compounds that Up-Regulate Insulin Promoter Activity i... | - |
| Unchecked | EC50 | = | 9060.0 | nM | 5.04 | PUBCHEM_BIOASSAY: Counterscreen for Fluorescence in GFP-Spectra Wavelengths Caus... | - |
| Zinc finger protein mex-5 | EC50 | = | 11560.0 | nM | 4.94 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
| RNA-binding protein pos-1 | EC50 | = | 12499.0 | nM | 4.9 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
Data from ChEMBL 36 via Core Engine