Compound Detail
CHEMBL1405447
VITAMIN K3H2 Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1405447 |
| Name | VITAMIN K3H2 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZJTLZYDQJHKRMQ-UHFFFAOYSA-N |
1
Targets
5
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
174.2
MW (Da)
2.56
ALogP
2
HBA
2
HBD
40.5
PSA (Ų)
0.60
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 5 meas. best 5.76
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.76 | 5.41 | 1754.8 | 5 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 1754.8 | nM | 5.76 | PubChem BioAssay. alkaline phosphatase stimulation in WNT3A conditioned C2C12 ce... | - |
| Unchecked | IC50 | = | 2457.1 | nM | 5.61 | PubChem BioAssay. Decreased HeLa cell count-IC50. (Class of assay: confirmator... | - |
| Unchecked | IC50 | = | 4394.6 | nM | 5.36 | PubChem BioAssay. nuclear beta catenin stimulation in WNT3A conditioned C2C12 ce... | - |
| Unchecked | IC50 | = | 4893.3 | nM | 5.31 | PubChem BioAssay. VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area de... | - |
| Unchecked | IC50 | = | 9854.44 | nM | 5.01 | PubChem BioAssay. VEGF stimulated ADSC/ECFC co-culture nuclear area decrease (vi... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17629592 | 10.1016/j.ejmech.2007.05.007 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine