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Compound Detail

CHEMBL1406312

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Cc1ccc(NCCc2c([N+](=O)[O-])cc([N+](=O)[O-])cc2[N+](=O)[O-])cc1

Basic Information

ChEMBL ID CHEMBL1406312
Phase Preclinical
Structure Type MOL
InChI Key FCMHTNNNOIOVQU-UHFFFAOYSA-N
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

346.3
MW (Da)
3.37
ALogP
7
HBA
1
HBD
141.4
PSA (Ų)
0.60
QED
0
Ro5 Violations
7
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C15H14N4O6
MW 346.30
Aromatic Rings 2
Heavy Atoms 25
NP-Likeness -1.06

Activity Summary

EC50 1 meas. best 6.99
IC50 1 meas. best 5.53

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
EC50 6.99 6.99 103.0 1
Unchecked
CHEMBL612545
IC50 5.53 5.53 2979.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine