Compound Detail
CHEMBL1428589
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Basic Information
| ChEMBL ID | CHEMBL1428589 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZARNIAJBXGUBFV-UHFFFAOYSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
420.5
MW (Da)
2.39
ALogP
6
HBA
2
HBD
125.0
PSA (Ų)
0.77
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 4.55
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 4.55 | 4.32 | 28345.0 | 2 |
| Endoribonuclease toxin MazF CHEMBL1795096 | EC50 | 4.44 | 4.44 | 36100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 28345.0 | nM | 4.55 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Inhibito... | - |
| Endoribonuclease toxin MazF | EC50 | = | 36100.0 | nM | 4.44 | PUBCHEM_BIOASSAY: Dose response confirmation uHTS hits for MazEF TA System activ... | - |
| Unchecked | EC50 | = | 81661.0 | nM | 4.09 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Inhi... | - |
Data from ChEMBL 36 via Core Engine