Compound Detail
CHEMBL1438291
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1438291 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WUFDHUTXBVGMFP-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
446.5
MW (Da)
5.10
ALogP
5
HBA
1
HBD
79.7
PSA (Ų)
0.51
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.53
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Major prion protein CHEMBL4869 | IC50 | 5.53 | 5.53 | 2956.0 | 1 |
| NS3 CHEMBL1293269 | IC50 | 5.24 | 5.24 | 5771.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Major prion protein | IC50 | = | 2956.0 | nM | 5.53 | PubChem BioAssay. TRFRET-based cell-based high throughput dose response assay to... | - |
| NS3 | IC50 | = | 5771.0 | nM | 5.24 | PUBCHEM_BIOASSAY: Fluorescence-based biochemical high throughput dose response a... | - |
Data from ChEMBL 36 via Core Engine