Compound Detail
CHEMBL144345
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Basic Information
| ChEMBL ID | CHEMBL144345 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LBVZDXOTAWYART-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
278.4
MW (Da)
3.64
ALogP
2
HBA
0
HBD
32.7
PSA (Ų)
0.83
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.38
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Progesterone receptor CHEMBL208 | IC50 | 6.38 | 6.38 | 416.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Progesterone receptor | IC50 | = | 416.0 | nM | 6.38 | Binding affinity against Progesterone receptor in human TE85 osteosarcoma cells ... | 8523400 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8523400 | 10.1021/jm00025a004 | Progesterone receptor | 1 |
| 8523399 | 10.1021/jm00025a003 | Progesterone receptor | 1 |
Data from ChEMBL 36 via Core Engine