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Compound Detail

CHEMBL1452245

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Cc1ccc(NC(=O)c2ccc3snnc3c2)cc1

Basic Information

ChEMBL ID CHEMBL1452245
Phase Preclinical
Structure Type MOL
InChI Key XRUQKEZPNNBBGO-UHFFFAOYSA-N
1
Targets
5
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

269.3
MW (Da)
3.25
ALogP
4
HBA
1
HBD
54.9
PSA (Ų)
0.78
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C14H11N3OS
MW 269.33
Aromatic Rings 3
Heavy Atoms 19
NP-Likeness -2.32

Activity Summary

EC50 5 meas. best 6.73

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
EC50 6.73 5.85 185.0 5

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine