Compound Detail
CHEMBL1479604
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Basic Information
| ChEMBL ID | CHEMBL1479604 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KZUOLEDMGFKECT-CMDGGOBGSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
420.9
MW (Da)
3.29
ALogP
5
HBA
0
HBD
67.7
PSA (Ų)
0.71
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.94
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Signal transducer and activator of transcription 1-alpha/beta CHEMBL6101 | IC50 | 4.94 | 4.94 | 11420.0 | 1 |
| Signal transducer and activator of transcription 3 CHEMBL4026 | IC50 | 4.43 | 4.43 | 37140.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Signal transducer and activator of transcription 1-alpha/beta | IC50 | = | 11420.0 | nM | 4.94 | PUBCHEM_BIOASSAY: Dose response cell-based assay to measure STAT1 inhibition. (C... | - |
| Signal transducer and activator of transcription 3 | IC50 | = | 37140.0 | nM | 4.43 | PUBCHEM_BIOASSAY: Dose response counterscreen for STAT1 inhibitors: cell-based h... | - |
Data from ChEMBL 36 via Core Engine