Compound Detail
CHEMBL1492152
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1492152 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MOJJOJXUACHANH-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
377.4
MW (Da)
2.68
ALogP
8
HBA
2
HBD
102.0
PSA (Ų)
0.61
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Psychosine receptor CHEMBL3714081 | EC50 | 6.3 | 6.3 | 501.2 | 1 |
| Unchecked CHEMBL612545 | EC50 | 5.2 | 5.2 | 6309.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Psychosine receptor | EC50 | = | 501.19 | nM | 6.3 | Antagonist activity against GPR65 (unknown origin) transfected in human HEK293T ... | 26550826 |
| Unchecked | EC50 | = | 6309.57 | nM | 5.2 | Antagonist activity against GPR65 D153A mutant (unknown origin) transfected in h... | 26550826 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 26550826 | 10.1038/nature15699 | Psychosine receptor | 5 |
| 26550826 | 10.1038/nature15699 | Unchecked | 5 |
Data from ChEMBL 36 via Core Engine