Compound Detail
CHEMBL149556
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL149556 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ROPLRWWORDJINQ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
205.2
MW (Da)
0.54
ALogP
3
HBA
1
HBD
74.7
PSA (Ų)
0.68
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human rhinovirus A protease CHEMBL2857 | Ki | 5.0 | 5.0 | 10000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human rhinovirus A protease | Ki | = | 10000.0 | nM | 5.0 | Inhibition of human rhinovirus 3C protease | 8978838 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8978838 | 10.1021/jm960603e | HeLa | 2 |
| 11384246 | 10.1021/jm0100537 | Caspase-3 | 1 |
| 8978838 | 10.1021/jm960603e | Human rhinovirus A protease | 1 |
| 16759084 | 10.1021/jm0602357 | Replicase polyprotein 1a | 1 |
| 32798789 | 10.1016/j.ejmech.2020.112702 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine