Compound Detail
CHEMBL1497574
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1497574 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BQHCBHGIMFAGFX-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
337.4
MW (Da)
3.29
ALogP
5
HBA
1
HBD
75.4
PSA (Ų)
0.72
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 6.09
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Signal transducer and activator of transcription 3 CHEMBL4026 | EC50 | 6.09 | 6.09 | 803.5 | 1 |
| Unchecked CHEMBL612545 | EC50 | 5.27 | 5.27 | 5370.0 | 1 |
| Signal transducer and activator of transcription 1-alpha/beta CHEMBL6101 | EC50 | 5.0 | 5.0 | 10006.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Signal transducer and activator of transcription 3 | EC50 | = | 803.53 | nM | 6.09 | PUBCHEM_BIOASSAY: Late stage counterscreen results from the probe development ef... | - |
| Unchecked | EC50 | = | 5370.0 | nM | 5.27 | PUBCHEM_BIOASSAY: Counterscreen for Fluorescence in GFP-Spectra Wavelengths Caus... | - |
| Signal transducer and activator of transcription 1-alpha/beta | EC50 | = | 10006.0 | nM | 5.0 | PUBCHEM_BIOASSAY: Late stage results from the probe development effort to identi... | - |
Data from ChEMBL 36 via Core Engine