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Compound Detail

CHEMBL1503688

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Nc1ccccc1-[n+]1c(-c2ccccc2)cc(-c2ccccc2)cc1-c1ccccc1.[O-][Cl+3]([O-])([O-])[O-]

Basic Information

ChEMBL ID CHEMBL1503688
Phase Preclinical
Structure Type MOL
InChI Key JKLJKBYRSNZRRV-UHFFFAOYSA-M
Parent Compound CHEMBL1622467
Active Moiety CHEMBL1622467
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

399.5
MW (Da)
6.55
ALogP
1
HBA
1
HBD
29.9
PSA (Ų)
0.27
QED
1
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C29H23ClN2O4
MW 498.97
Aromatic Rings 5
Heavy Atoms 31
NP-Likeness -0.13

Activity Summary

EC50 2 meas. best 6.94

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
EC50 6.94 6.505 114.0 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine