Compound Detail
CHEMBL1505420
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1505420 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RYEGSNCAVWIDPF-BMRADRMJSA-N |
3
Targets
3
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
408.4
MW (Da)
1.57
ALogP
6
HBA
4
HBD
127.8
PSA (Ų)
0.33
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.11
EC50 1 meas. best 4.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Aminopeptidase N CHEMBL4117 | IC50 | 5.11 | 5.11 | 7800.0 | 1 |
| Heat shock factor protein 1 CHEMBL5313 | EC50 | 4.52 | 4.52 | 30185.0 | 1 |
| Leucine aminopeptidase CHEMBL1293313 | IC50 | 4.33 | 4.33 | 47310.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Aminopeptidase N | IC50 | = | 7800.0 | nM | 5.11 | PUBCHEM_BIOASSAY: Inhibitors of Plasmodium falciparum M1- Family Alanyl Aminopep... | - |
| Heat shock factor protein 1 | EC50 | = | 30185.0 | nM | 4.52 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Inhi... | - |
| Leucine aminopeptidase | IC50 | = | 47310.0 | nM | 4.33 | PUBCHEM_BIOASSAY: Inhibitors of Plasmodium falciparum M17- Family Leucine Aminop... | - |
Data from ChEMBL 36 via Core Engine