Compound Detail
CHEMBL1519408
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Basic Information
| ChEMBL ID | CHEMBL1519408 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DLKRCLMWGBCNOC-RSGUCCNWSA-N |
| Parent Compound | CHEMBL1623103 |
| Active Moiety | CHEMBL1623103 |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
303.3
MW (Da)
3.68
ALogP
4
HBA
1
HBD
78.9
PSA (Ų)
0.59
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 4.76
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Runt-related transcription factor 1/Core-binding factor subunit beta CHEMBL2093862 | IC50 | 4.76 | 4.6533 | 17400.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Runt-related transcription factor 1/Core-binding factor subunit beta | IC50 | = | 17400.0 | nM | 4.76 | PUBCHEM_BIOASSAY: Identification of compounds inhibiting the binding between the... | - |
| Runt-related transcription factor 1/Core-binding factor subunit beta | IC50 | = | 23600.0 | nM | 4.63 | PUBCHEM_BIOASSAY: uHTS identification of compounds inhibiting the binding betwee... | - |
| Runt-related transcription factor 1/Core-binding factor subunit beta | IC50 | = | 26648.0 | nM | 4.57 | PUBCHEM_BIOASSAY: Confirmation of compounds inhibiting the binding between the R... | - |
Data from ChEMBL 36 via Core Engine