Compound Detail
CHEMBL1523792
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Basic Information
| ChEMBL ID | CHEMBL1523792 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QFGQXFPLOJFEDK-UHFFFAOYSA-N |
2
Targets
6
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
310.3
MW (Da)
3.86
ALogP
6
HBA
2
HBD
99.9
PSA (Ų)
0.56
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 5.11
IC50 3 meas. best 5.65
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.65 | 5.575 | 2220.0 | 2 |
| Female germline-specific tumor suppressor gld-1 CHEMBL1293302 | IC50 | 5.21 | 5.21 | 6228.0 | 1 |
| Unchecked CHEMBL612545 | EC50 | 5.11 | 5.0733 | 7690.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 2220.0 | nM | 5.65 | PUBCHEM_BIOASSAY: HCS for Compounds that Down-Regulate Insulin Promoter Activity... | - |
| Unchecked | IC50 | = | 3200.0 | nM | 5.5 | PUBCHEM_BIOASSAY: HTS Counterscreen for Detection of Compound Cytotoxicity in MI... | - |
| Female germline-specific tumor suppressor gld-1 | IC50 | = | 6228.0 | nM | 5.21 | PUBCHEM_BIOASSAY: Fluorescence polarization-based biochemical high throughput do... | - |
| Unchecked | EC50 | = | 7690.0 | nM | 5.11 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Inhibito... | - |
| Unchecked | EC50 | = | 8607.0 | nM | 5.07 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Inhi... | - |
| Unchecked | EC50 | = | 9181.0 | nM | 5.04 | PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Inhibito... | - |
Data from ChEMBL 36 via Core Engine