Compound Detail
CHEMBL152617
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Basic Information
| ChEMBL ID | CHEMBL152617 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YZSKSIBYNQHPBG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
368.5
MW (Da)
2.18
ALogP
5
HBA
1
HBD
52.0
PSA (Ų)
0.88
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.85
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Adrenergic receptor alpha-1 CHEMBL1907610 | Ki | 6.85 | 6.85 | 140.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Adrenergic receptor alpha-1 | Ki | = | 140.0 | nM | 6.85 | The compound was tested for its binding affinity towards Alpha-1 adrenergic rece... | 1346653 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1346653 | 10.1021/jm00081a018 | Rattus norvegicus | 1 |
| 1346653 | 10.1021/jm00081a018 | D(2) dopamine receptor | 1 |
| 1346653 | 10.1021/jm00081a018 | Adrenergic receptor alpha-1 | 1 |
Data from ChEMBL 36 via Core Engine