Compound Detail
CHEMBL1528266
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Basic Information
| ChEMBL ID | CHEMBL1528266 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IBIFWURDGNEUJG-UHFFFAOYSA-N |
3
Targets
4
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
360.7
MW (Da)
4.19
ALogP
5
HBA
2
HBD
80.1
PSA (Ų)
0.46
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.25
IC50 2 meas. best 4.78
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Streptokinase A CHEMBL1293228 | EC50 | 5.25 | 5.12 | 5570.0 | 2 |
| Epstein-Barr nuclear antigen 1 CHEMBL1293281 | IC50 | 4.78 | 4.78 | 16774.0 | 1 |
| Lytic switch protein BZLF1 CHEMBL1293280 | IC50 | 4.63 | 4.63 | 23504.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Streptokinase A | EC50 | = | 5570.0 | nM | 5.25 | PUBCHEM_BIOASSAY: Absorbance Microorganism-Based Dose Response HTS to Identify I... | - |
| Streptokinase A | EC50 | = | 10357.0 | nM | 4.99 | PUBCHEM_BIOASSAY: Absorbance Microorganism-Based Dose Response Follow up to Iden... | - |
| Epstein-Barr nuclear antigen 1 | IC50 | = | 16774.0 | nM | 4.78 | PUBCHEM_BIOASSAY: Fluorescence polarization-based biochemical high throughput do... | - |
| Lytic switch protein BZLF1 | IC50 | = | 23504.0 | nM | 4.63 | PUBCHEM_BIOASSAY: Counterscreen for inhibitors of EBNA-1: fluorescence polarizat... | - |
Data from ChEMBL 36 via Core Engine