Compound Detail
CHEMBL1543210
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Basic Information
| ChEMBL ID | CHEMBL1543210 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZPRVBPBTEKAMCQ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
421.4
MW (Da)
3.72
ALogP
5
HBA
2
HBD
103.1
PSA (Ų)
0.56
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein CHEMBL3885546 | EC50 | 5.26 | 5.26 | 5470.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein | EC50 | = | 5470.0 | nM | 5.26 | PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS hits for small molecule ago... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30109001 | 10.1039/C8MD00219C | Unchecked | 2 |
| 30109001 | 10.1039/C8MD00219C | A549 | 1 |
| 30109001 | 10.1039/C8MD00219C | HCT-116 | 1 |
| 30109001 | 10.1039/C8MD00219C | ZR-75-30 | 1 |
Data from ChEMBL 36 via Core Engine