Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL1563624

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
CN1CCc2c(sc3c2C(=O)NC(c2ccccn2)N3)C1

Basic Information

ChEMBL ID CHEMBL1563624
Phase Preclinical
Structure Type MOL
InChI Key CMBLACABHYQMGR-UHFFFAOYSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

300.4
MW (Da)
1.99
ALogP
5
HBA
2
HBD
57.3
PSA (Ų)
0.85
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C15H16N4OS
MW 300.39
Aromatic Rings 2
Heavy Atoms 21
NP-Likeness -1.34

Activity Summary

EC50 2 meas. best 4.84

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Zinc finger protein mex-5
CHEMBL1293319
EC50 4.84 4.84 14300.0 1
RNA-binding protein pos-1
CHEMBL1293304
EC50 4.82 4.82 15079.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine