Compound Detail
CHEMBL157316
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL157316 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HYPWJFJGJZTCJY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
411.4
MW (Da)
4.67
ALogP
5
HBA
2
HBD
98.3
PSA (Ų)
0.43
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.85
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Coagulation factor X CHEMBL244 | Ki | 5.85 | 5.85 | 1400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Coagulation factor X | Ki | = | 1400.0 | nM | 5.85 | Inhibition of human Coagulation factor X was determined | 14667222 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 14667222 | 10.1021/jm030288d | Coagulation factor X | 1 |
Data from ChEMBL 36 via Core Engine