Compound Detail
CHEMBL15732
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Basic Information
| ChEMBL ID | CHEMBL15732 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BSKHPKMHTQYZBB-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
93.1
MW (Da)
1.39
ALogP
1
HBA
0
HBD
12.9
PSA (Ų)
0.47
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 3 meas. best 7.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Neuronal acetylcholine receptor CHEMBL2094110 | Kd | 7.3 | 7.3 | 50.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Neuronal acetylcholine receptor | Kd | = | 50.0 | nM | 7.3 | Ability to enhance the binding of (+/-)-[3H]nicotine to the rat brain P2 fractio... | 4032427 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 4032427 | 10.1021/jm00147a021 | Neuronal acetylcholine receptor | 7 |
| - | 10.6019/CHEMBL4651402 | SARS-CoV-2 | 2 |
| 7199089 | 10.1021/jm00142a006 | Thromboxane-A synthase | 1 |
| 114658 | 10.1021/jm00195a026 | No relevant target | 1 |
| 817022 | 10.1021/jm00226a007 | No relevant target | 1 |
| 37014977 | 10.1021/acs.jmedchem.2c02015 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine