Compound Detail
CHEMBL159346
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Basic Information
| ChEMBL ID | CHEMBL159346 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KQLYVTCAUKHNRW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
161.2
MW (Da)
2.07
ALogP
1
HBA
1
HBD
26.0
PSA (Ų)
0.71
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 5.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2B CHEMBL323 | Kd | 5.6 | 5.6 | 2511.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2B | Kd | = | 2511.89 | nM | 5.6 | The binding affinity to 5-hydroxytryptamine 2B receptor of rat fundus | 7086824 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7086824 | 10.1021/jm00343a013 | 5-hydroxytryptamine receptor 2B | 1 |
Data from ChEMBL 36 via Core Engine