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Compound Detail

CHEMBL1598570

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COc1ccc(NC(=O)NS(=O)(=O)c2ccc(C)cc2)cn1

Basic Information

ChEMBL ID CHEMBL1598570
Phase Preclinical
Structure Type MOL
InChI Key LUHPQZVSQHWZDR-UHFFFAOYSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

321.4
MW (Da)
1.91
ALogP
5
HBA
2
HBD
97.4
PSA (Ų)
0.90
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C14H15N3O4S
MW 321.36
Aromatic Rings 2
Heavy Atoms 22
NP-Likeness -2.06

Activity Summary

EC50 2 meas. best 5.62

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
RNA-binding protein pos-1
CHEMBL1293304
EC50 5.62 5.62 2370.0 1
Zinc finger protein mex-5
CHEMBL1293319
EC50 5.62 5.62 2381.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine