Compound Detail
CHEMBL1650564
CYMELARSEN Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1650564 |
| Name | CYMELARSEN |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MGEOLZFMLHYCFZ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
7
Publications
0
Known Names
Molecular Properties
428.4
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 4.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Adenosine transporter 1 CHEMBL2601 | Ki | 4.64 | 4.64 | 22900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Adenosine transporter 1 | Ki | = | 22900.0 | nM | 4.64 | Compound was tested for inhibition of Adenosine transporter P2 type by using [2-... | 10890161 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19786604 | 10.1128/aac.00422-09 | Trypanosoma evansi | 5 |
| 10890161 | 10.1016/s0960-894x(00)00233-x | Adenosine transporter 1 | 1 |
| 21985060 | 10.1021/np2004825 | Plasmodium falciparum | 1 |
| 21985060 | 10.1021/np2004825 | Leishmania donovani | 1 |
| 21985060 | 10.1021/np2004825 | Trypanosoma brucei brucei | 1 |
| 21985060 | 10.1021/np2004825 | Vero | 1 |
| - | 10.6019/CHEMBL3988181 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine