Compound Detail
CHEMBL1650611
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Basic Information
| ChEMBL ID | CHEMBL1650611 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | STUQITWXBMZUGY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
9
Publications
0
Known Names
Molecular Properties
144.2
MW (Da)
0.18
ALogP
5
HBA
3
HBD
66.2
PSA (Ų)
0.36
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 3.55
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Bromodomain adjacent to zinc finger domain protein 2B CHEMBL1741220 | IC50 | 3.55 | 3.55 | 279000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Bromodomain adjacent to zinc finger domain protein 2B | IC50 | = | 279000.0 | nM | 3.55 | Displacement of biotinylated H3Kac14 peptide from His6-tagged human BAZ2B expres... | 24304323 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24304323 | 10.1021/jm401582c | Bromodomain adjacent to zinc finger domain protein 2B | 7 |
| 21189019 | 10.1021/jm101266s | Lethal factor | 1 |
| 21189019 | 10.1021/jm101266s | Polyunsaturated fatty acid 5-lipoxygenase | 1 |
| 21189019 | 10.1021/jm101266s | Stromelysin-1 | 1 |
| 21189019 | 10.1021/jm101266s | Interstitial collagenase | 1 |
| 21189019 | 10.1021/jm101266s | Matrix metalloproteinase-9 | 1 |
| 21189019 | 10.1021/jm101266s | Neutrophil collagenase | 1 |
| 21189019 | 10.1021/jm101266s | 72 kDa type IV collagenase | 1 |
| 21189019 | 10.1021/jm101266s | Tyrosinase | 1 |
Data from ChEMBL 36 via Core Engine