Compound Detail
CHEMBL1651329
DICHOTOMIDE X Enter ChEMBL ID:
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C/C=C(/C)C(=O)O[C@@H](C)c1nc(C(=O)N/C=C/C(=O)OC)cc2c1[nH]c1ccccc12
Basic Information
| ChEMBL ID | CHEMBL1651329 |
| Name | DICHOTOMIDE X |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FYJIMBXWGFOPJQ-QICPNHSRSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
421.4
MW (Da)
3.70
ALogP
6
HBA
2
HBD
110.4
PSA (Ų)
0.46
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.95
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RAW264.7 CHEMBL612557 | IC50 | 4.95 | 4.95 | 11300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RAW264.7 | IC50 | = | 11300.0 | nM | 4.95 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-... | 21090796 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21090796 | 10.1021/np1003627 | RAW264.7 | 1 |
Data from ChEMBL 36 via Core Engine