Compound Detail
CHEMBL166797
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Basic Information
| ChEMBL ID | CHEMBL166797 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KDJCJVULTPFHRD-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
344.2
MW (Da)
5.17
ALogP
4
HBA
1
HBD
57.9
PSA (Ų)
0.71
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Proto-oncogene tyrosine-protein kinase Src CHEMBL267 | IC50 | 6.5 | 6.5 | 320.0 | 1 |
| Molecular identity unknown CHEMBL612546 | IC50 | 6.5 | 6.5 | 320.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Proto-oncogene tyrosine-protein kinase Src | IC50 | = | 320.0 | nM | 6.5 | Inhibitory activity against human c-Src Kinase was measured using ELISA assay | 11262092 |
| Molecular identity unknown | IC50 | = | 320.0 | nM | 6.5 | Inhibition of tyrosine kinase (unknown origin) | 38781921 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11262092 | 10.1021/jm000420z | Proto-oncogene tyrosine-protein kinase Src | 1 |
| 38781921 | 10.1016/j.ejmech.2024.116364 | Molecular identity unknown | 1 |
Data from ChEMBL 36 via Core Engine