Compound Detail
CHEMBL1698011
TRENBOLONE ACETATE 🧪 Phase II
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🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL1698011 |
| Name | TRENBOLONE ACETATE |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | CMRJPMODSSEAPL-FYQPLNBISA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
2
Publications
9
Known Names
Molecular Properties
312.4
MW (Da)
3.90
ALogP
3
HBA
0
HBD
43.4
PSA (Ų)
0.69
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Single Enantiomer |
Activity Summary
EC50 1 meas. best 4.29
Kd 1 meas. best 4.04
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | EC50 | 4.29 | 4.29 | 51000.0 | 1 |
| Polymerase acidic protein CHEMBL1169598 | Kd | 4.04 | 4.04 | 90700.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | EC50 | = | 51000.0 | nM | 4.29 | Antiviral activity against Influenza A virus A/PR/8/34 (H1N1) infected in MDCK c... | 27046062 |
| Polymerase acidic protein | Kd | = | 90700.0 | nM | 4.04 | Binding affinity to PA cavity of recombinant Influenza A virus A/PR/8/34(H1N1) P... | 27046062 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 27046062 | 10.1021/acs.jmedchem.5b01474 | NON-PROTEIN TARGET | 1 |
| 27046062 | 10.1021/acs.jmedchem.5b01474 | Polymerase acidic protein | 1 |
Data from ChEMBL 36 via Core Engine