Compound Detail
CHEMBL1705379
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Basic Information
| ChEMBL ID | CHEMBL1705379 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OHKNSXMQSNDXAI-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
203.3
MW (Da)
1.92
ALogP
5
HBA
1
HBD
39.2
PSA (Ų)
0.59
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.74
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Melanocortin receptor 4 CHEMBL259 | IC50 | 4.74 | 4.74 | 18201.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 4.35 | 4.35 | 44672.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Melanocortin receptor 4 | IC50 | = | 18201.0 | nM | 4.74 | PUBCHEM_BIOASSAY: TRFRET-based cell-based high throughput dose response assay fo... | - |
| Unchecked | IC50 | = | 44672.0 | nM | 4.35 | PUBCHEM_BIOASSAY: Counterscreen for biased ligands (antagonists) of the melanoco... | - |
Data from ChEMBL 36 via Core Engine