Compound Detail
CHEMBL175301
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)OC(CCCN1CC[C@@H]2C(C1)c1cc(F)ccc1N2c1ccc(F)cc1)c1ccc(F)cc1
Basic Information
| ChEMBL ID | CHEMBL175301 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QXBBLTVHGIMTJE-ZLXHKOCKSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
699.8
MW (Da)
8.61
ALogP
6
HBA
1
HBD
71.1
PSA (Ų)
0.16
QED
2
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rattus norvegicus CHEMBL376 | IC50 | 7.66 | 7.66 | 22.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Rattus norvegicus | IC50 | = | 22.0 | nM | 7.66 | Inhibition of [3H]spiroperidol binding to rat striatal membrane using 0.5 nM lig... | 6105220 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 6105220 | 10.1021/jm00182a025 | Rattus norvegicus | 4 |
Data from ChEMBL 36 via Core Engine