Compound Detail
CHEMBL1761093
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Basic Information
| ChEMBL ID | CHEMBL1761093 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PWBFUKYLAOVVJB-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
224.1
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 4.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Beta-lactamase CHEMBL2725 | Ki | 4.7 | 4.7 | 19790.0 | 1 |
| Unchecked CHEMBL612545 | Ki | 4.59 | 4.59 | 25630.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Beta-lactamase | Ki | = | 19790.0 | nM | 4.7 | Inhibition of Enterobacter cloacae P99 beta-lactamase AmpC P99 using nitrocefin ... | 21392987 |
| Unchecked | Ki | = | 25630.0 | nM | 4.59 | Inhibition of beta-lactamase CMY-2 using nitrocefin as substrate after 30 mins b... | 21392987 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21392987 | 10.1016/j.bmcl.2011.02.024 | Unchecked | 3 |
| 21392987 | 10.1016/j.bmcl.2011.02.024 | Beta-lactamase | 1 |
Data from ChEMBL 36 via Core Engine